ncRNA name | hsa-miR-383 |
ncRNA Category | miRNA |
Disease name | diabetic retinopathy (DR) |
Species | Homo sapiens |
Tissues/Cell_line | human RPE cell line ARPE-19 |
Methods | qPCR, transfection, MTT assay, apoptosis analysis, Western blot |
Expression pattern | up-regulated |
Functional description | miR-383 upregulation accounts for high glucose-induced oxidative stress and apoptosis in RPE cells by repressing PRDX3 expression. |
PubMed ID | 28559987 |
Year | 2017 |
Title | microRNA-383 mediates high glucose-induced oxidative stress and apoptosis in retinal pigment epithelial cells by repressing peroxiredoxin 3. |
Drug-related ncRNA | NO |
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